The presented non-invasive electrode features a pressure compensation system designed to improve the detection of small electric currents at characteristic points on the skin. The force sensing element allows to operate over a wide range of values and to obtain measurements insensitive to pressure’s fluctuations. The main components of the realized instrument have been described in the paper and results of measurements have been provided showing that small electric currents can be measured at characteristic points on the skin in a replicable
manner. The proportionality between these currents and the homeostatic level of the cells of the organ correlated with the selected points needs to be further investigated in order to understand if the correct evaluation of the magnitude of these currents can be meaningful for diagnostic purposes.